Technology Profiles
 Profile Detail
Customized Transgenic Solutions transgenic animal creation for a wide range of specialty needs. (12 HU 5010 3NV9)
A leading biotechnology SME in Hungary, offers the ability to create transgenic rabbit and rat models via microinjecting large genomic fragments at its state-of-the-art facility. Proven track record with some of the world's leading developers of rabbit and rat models. The technology ensures high level tissue and developmental stage specific expression of the transgene.
Pharma manufacturers and R&D partners are sought for technical cooperation, commercial or manufacturing agreements.
Country: Hungary
Type: OFFER
Date: 19.01.2012
The Hungarian company has experience and references in creating transgenic mice, rat and rabbit with microinjecting large genomic fragments. Rabbit transgenesis is the specialty of the company.
It is suitable to create models of complex human diseases. The animals are created and kept in high standard SPF (Specific Pathogen Free) mouse and rat facility and MD (Minimal disease) rabbit housing.
The company's recent studies showed that a transgenic rabbit model created with large genomic fragment BAC (Bacterial artificial chromosome) transgenesis offers special advantage in polyclonal antibody production, because the transgene expressed at high level. The BAC clones can be grown and modified in Escherichia coli with a technology, which offers fast alternative to the knockout technology in embryonic stem cells.
The company has the necessary experts and special equipment to provide this technology in the frame of service or collaboration agreements.
Innovative Aspects:
There are limited number of groups in the world that can make transgenic rabbits, and the demand for these animal models has increased recently to satisfy the need for superior models for certain diseases including cardiovascular, pulmonary and ophthalmic indications.
The advantage of this technology that ensures:
- high level tissue and developmental stage specific expression of the transgene
- Interactive transgene design
- rapid turnaround time
- efficient world-wide delivery
Degree of development:
Patents/Rights: Secret know-how
Requested Cooperation: Engineering, Adaptation to specific needs, New way to use an existing production line
- Type of partner sought:
R&D institutions, SMEs, large pharma or diagnostics manufacturers
- Specific area of activity of the partner:
- preclinical test phase of novel pharmaceutical products (pharma, clinics)
- production of pharmaceutically active protein products through biopharming (biotech companies
- Task to be performed by the partner sought:
preclinical testing of the created transgenic animal
Type of Organisation:
Status: NEW
| 
