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Antigens for diagnostics of Q fever and other rickettsial infections (04 SK SKBB 0BGF)
A Slovak institute has developed new highly purified corpuscular antigens enabling specific detection of antibodies against Coxiella burnetii and some other rickettsia in serum, plasma and milk samples of animals and in human sera. The antigen preparations enable both to determine the origin of the disease and to propose an efficient medical treatment. They are open for license and/or joint venture.
Country: Slovakia Type: OFFER Date: 20.04.2010
A Slovak institute active in the virology area has developed new highly purified corpuscular antigens enabling rapid, simple, sensitive and specific detection of antibodies against Coxiella burnetii and some other rickettsia in serum, plasma and milk samples of animals and in human sera. The antigen preparations enable both to determine the origin of the disease and to propose an efficient medical treatment.

Antigens for diagnostics of Q fever:
- Antigen for complement fixation (CF) test
- Coxiella burnetii phase I antigen for CF test
- Antigen for microagglutination (MA) test
- Coxiella burnetii phase I antigen for MA test
- Antigens for microimmunofluorescence (MIF) test
- Phase II antigen
- Phase I antigen
- Antigens for ELISA (enzyme-linked immunosorbent assay)
- Antigen for screening sera, detecting phase I and phase II antibodies
- Phase II antigen
- Phase I antigen

Other rickettsial antigens:
- Rickettsia typhi antigen for MIF test
- Rickettsia conorii antigen for MIF test
- Spotted fever group rickettsiae antigen for CF test or ELISA
- Typhus group rickettsiae antigen for CF test or ELISA

An efficient corpuscular vaccine for prophylaxis against coxiellosis in livestock is also available.
R&D has been completed. The antigen preparations and corpuscular vaccine have been used successfully in the field.

Innovative Aspects:
Highly purified corpuscular antigens enabling rapid, simple, sensitive and specific detection of antibodies against Coxiella burnetii and some other rickettsia in serum, plasma and milk samples of animals and in human sera. The antigen preparations enable both to determine the origin of the disease and to propose an efficient medical treatment.
 
Degree of development:
Patents/Rights: Secret know-how
Requested Cooperation: License Agreement, Joint Venture Agreement
- Type of partner sought:
Institutes and institutions: hospitals, health centres, veterinary institutes, regional veterinary stations, etc.
Type of Organisation:
Status: UPDATE
 
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