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Absolute new structure for anti cancer derivate (08 DE 0855 0IQQ)
A German university developed a new group of metallocenophanes as potent cytostatic drugs.
The new compounds, which are obtained according to a new synthetic route, represent potential candidates for the medical treatment of tumor diseases. The benefits are high yields, positive results in cell cultures and easy access to pure compounds.
They look for industrial partners from the field of biotech or pharma interested either to license the new compounds or for joint-venture research projects.
Country: Germany
Type: OFFER
Date: 16.08.2011
A German university has developed a new group of metallocenophanes as potent cytostatic drugs.
The invention pertains to a new group of metallocenophanes as potent cytostatic drugs. The ferrocenophanes were designed by reductive coupling of special carbonyl groups with iron sandwich compounds.
The new compounds, which are obtained according to a new synthetic route, represent potential candidates for the medical treatment of tumor diseases.
Results on cell cultures (MTT Test= Diphenyltetrazoliumbromide) indicate pronounced cytotoxicity in pharmacologically relevant concentrations against L929 mouse fibroblasts and MCF-7 (=Human breast adenocarcinoma cell line) breast cancer cells.
Innovative Aspects:
- Absolute new structure for anti cancer derivate
- High yields
- Compounds new in pharmacological applications
- Easy access to pure compounds
- Positive results in cell cultures
Degree of development:
Patents/Rights: Patent(s) granted
Requested Cooperation: License Agreement, Joint Venture Agreement
- Type of partner sought: Industrial partner.
- Specific area of activity of the partner:
Pharma and / or biotechnology companies.
- Task to be performed:
The companies looked for should be interested either to license the new compounds, buy the patent or to work in a joint-venture research project.
Type of Organisation:
Status: NEW
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